Concordant Regulation of Gene Expression by Hypoxia and 2- Oxoglutarate Dependent Dioxygenase Inhibition; the Role of Hif-1α, Hif-2α and Other Pathways

From the Oxygen Sensing Group, The Henry Wellcome Building for Molecular Physiology, University of Oxford, Oxford OX3 7BN and Genomics Group, Wellcome Trust Centre for Human Genetics, The Henry Wellcome Building for Genomic Medicine, University of Oxford, Oxford, OX3 7BN Running title: Hypoxic gene regulation and 2-OG dependent dioxygenases * Address correspondence to: The Henry Wellcome Building for Molecular Physiology, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, United Kingdom. Phone: 44 (0)1865287788. Fax: 44 (0)1865-287787. E-mail: [email protected] or [email protected]